What are esomeprazole capsules?

ESOMEPRAZOLE (Nexium®) prevents the production of acid in the stomach. It is used to treat gastroesophageal reflux disease (GERD), ulcers, certain bacteria in the stomach, too much acid in the stomach, and inflammation of the esophagus. It can also be used to prevent ulcers in patients taking medicines called NSAIDs.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• liver disease
• an unusual or allergic reaction to esomeprazole, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I take this medicine?

Take esomeprazole capsules by mouth. Follow the directions on the prescription label. Swallow the capsules whole with a drink of water; do not crush, break or chew. The capsules can be opened and the contents sprinkled on applesauce or yogurt, given with fruit juices, or swallowed immediately with water. Do not crush the contents into the food. Esomeprazole works best if taken on an empty stomach at least one hour before a meal. Take your doses at regular intervals. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, just take your next scheduled dose when it is due. Do not use double or extra doses.

What drug(s) may interact with esomeprazole?

• ampicillin
• diazepam
• digoxin
• iron salts
• itraconazole, ketoconazole, voriconazole, or other prescription medicines for fungus or yeast infections
• phenytoin
• warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking esomeprazole?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• chest pain or tightness
• dark yellow or brown urine
• shortness of breath
• skin rash
• unusual tiredness or fatigue

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• headache
• diarrhea or constipation
• flatulence (gas)
• nausea/vomiting
• dry mouth

What should I watch for while taking esomeprazole?

It can take several days of therapy with esomeprazole before your stomach pains improve. Check with your prescriber or health care professional if your condition does not improve, or if it gets worse. You can take antacids for the occasional relief of pain unless your prescriber or health care professional tells you otherwise.

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.